Eosinophilic fasciitis

Eosinophilic fasciitis is a scleroderma-like syndrome of unknown cause characterized by inflammation followed later by sclerosis of the dermis, subcutis, and deep fascia. A marked eosinophilia is found in the early stage of disease and subsequently decreases.

Eosinophilic fasciitis affects adults and often occurs after strenuous physical activity. Patients do not have Raynaud's phenomenon or internal organ involvement.

Symptoms of Eosinophilic fasciitis

Several abnormalities have been associated with eosinophilic fasciitis and include aplastic anemia, myelodysplastic syndrome, and thrombocytopenia.

Treatment of Eosinophilic fasciitis

Spontaneous improvement and occasionally complete remission may occur after 2 to 5 years of disease. Some patients have persistent disease, while others are left with flexion contractures. Administration of glucocorticoids may provide symptomatic improvement and will decrease the eosinophilia. Improvement has been reported with the use of the H2 blocker cimetidine.

Amyloidosis
Connective tissue naevi
Dermatofibroma
Dermatofibrosarcoma protuberans
Ehler's Danlos syndrome
Elastosis perforans serpiginosa
Keloids & hypertrophic scars
Lipodystrophy
Lipoma
Mastocytoma
Neurofibroma
Pseudoxanthoma elasticum
Reactive perforating collagenosis
Striae (stretch marks)
Eosinophilic fasciitis
Erythema multiforme
Histiocytoses
Jessner's lymphocytic infiltrate
Langerhans cell histiocytosis
Lymphocytoma cutis
Lymphomatoid papulosis
Mastocytosis
Morphoea
Non-Langerhans cell histiocytosis
Panniculitis
Reticulohistiocytosis
Sweet's disease
Systemic sclerosis
Atypical mycobacterial infection
Granuloma faciale
Granuloma annulare
Cutaneous tuberculosis
Leprosy
Pyogenic granuloma
Sarcoidosis