Reactive perforating collagenosis

Reactive perforating collagenosis is a rare skin disorder in which abnormal collagen fibres extrude through the epidermis (outer layer of skin). The inherited form is a very rare condition with less than 50 cases reported in literature worldwide.

Reactive perforating collagenosis of renal failure/diabetes responsive to topical retinoic acid.

Cause of Reactive perforating collagenosis

The cause of abnormal collagen extruding through to the epidermis is unknown but lesions appear in response to superficial trauma such as scratching and are aggravated by cold weather.

Treatment of Reactive perforating collagenosis

Assessing treatments for perforating folliculitis is difficult. Although the condition is not uncommon, controlled therapeutic studies are not available. Treatments that have been used to treat and reduce lesions include Isotretinoin, Allopurinol, Doxycycline, Phototherapy.

Amyloidosis
Connective tissue naevi
Dermatofibroma
Dermatofibrosarcoma protuberans
Ehler's Danlos syndrome
Elastosis perforans serpiginosa
Keloids & hypertrophic scars
Lipodystrophy
Lipoma
Mastocytoma
Neurofibroma
Pseudoxanthoma elasticum
Reactive perforating collagenosis
Striae (stretch marks)
Eosinophilic fasciitis
Erythema multiforme
Histiocytoses
Jessner's lymphocytic infiltrate
Langerhans cell histiocytosis
Lymphocytoma cutis
Lymphomatoid papulosis
Mastocytosis
Morphoea
Non-Langerhans cell histiocytosis
Panniculitis
Reticulohistiocytosis
Sweet's disease
Systemic sclerosis
Atypical mycobacterial infection
Granuloma faciale
Granuloma annulare
Cutaneous tuberculosis
Leprosy
Pyogenic granuloma
Sarcoidosis